Insulin antagonises the growth hormone-mediated increase in the activity of phosphatidate phosphohydrolase in isolated rat hepatocytes

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THE EFFECTS OF GLUCAGON, INSULIN AND S TEROID HORMONES ON PHOSPHATIDATE PHOSPHOHYDROLASE ACTIVITY IN RAT LIVERS

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the effects of glucagon, insulin and s teroid hormones on phosphatidate phosphohydrolase activity in rat livers

the effects of steroid hormones, glucagon and insulin on rat liver phosphatidate phosphohydrolase (pap) activity were studied both in vitro and in vivo. incubation of rat hepatocytes with each hormone showed that dehydroepiandrosterone (dhea), progesterone and testosterone increase pap activity by 44.6, 37 and 36.9%, respectively. estradiol, however, decreased enzyme activity by 13.6% under the...

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ژورنال

عنوان ژورنال: FEBS Letters

سال: 1986

ISSN: 0014-5793

DOI: 10.1016/0014-5793(86)80663-9